Quinolines and derivatives
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Filtered Search Results
Ambeed 11bR 8 9 10 11 12 13 14 15Oct
(11bR)-8,9,10,11,12,13,14,15-Octahydro-N,Nbis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine, 1389329-66-1, 98%
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Medchemexpress LLC Benzyl-PEG5-amine | 86770-77-6 | 98.0% | C17H29NO5 | 50 MG
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Benzyl-PEG5-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Utilizes ubiquitin-proteasome system
- Selectively degrades target proteins
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Ambeed Anthracen9ylmethanamine
Anthracen-9-ylmethanamine, 2476-68-8, 97%
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000570030 TIPIRACIL-200MG
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Medchemexpress LLC Cyanine5.5 amine | 2097714-45-7 | 753.88 | C46H58Cl2N4O | 10 MG
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Cyanine5.5 amine is a near-infrared fluorescent dye bearing a reactive amine group for conjugation to biomolecules, nanoparticles, and polymers. It exhibits excitation at 680 nm and emission at 710 nm, making it suitable for low-background imaging in confocal and fluorescence microscopy applications.
- Near-infrared excitation and emission (680 nm/710 nm) for reduced autofluorescence.
- Amine functional group enables straightforward conjugation to proteins and nanoparticles.
- Appropriate for confocal and fluorescence microscopy and fluorescence-based tracking.
- Available in small and bulk pack sizes to support scouting experiments and scale-up.
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Medchemexpress LLC DBCO-amine | 1255942-06-3 | 99.1% | 276.34 g·mol-1 | C18H16N2O | 25 MG
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DBCO-amine is a dibenzocyclooctyne-containing amine reagent used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry. It is used as a small linker for bioconjugation and the synthesis of antibody-drug conjugates, and is typically handled and stored under anhydrous conditions and in organic solvent solutions for formulation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation.
- High purity suitable for synthetic and bioconjugation applications.
- Minimal spacer length reduces steric hindrance in conjugates.
- Compatible with common coupling chemistries for linker installation.
- Soluble in DMSO for straightforward formulation and handling.
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Chemscene CHEMSCENE
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5000579260 2 8-QUINOLINEDIOL 5G
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Enzo Life Sciences R-848, (25mg), CAS Number: 144875-48-9
Ligand for TLR7 and TLR8. R-848 is a selective ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Potent antitumor and antiviral compound. Stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 upregulation. Alternative Name: 4-Amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol. S 28463, Resiquimod, Formula: C17H22N4O2. MW: 314.4. CAS Number: 144875-48-9. Purity: ≥98% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in DMSO, dichloromethane, 100% or 5% methanol; poorly soluble in acetonitrile or ethyl acetate. Long Term Storage: -20°C
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Ambeed 4 6 2 3Methylbenzylidene hydra
4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate, 870087-36-8, 98%
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Medchemexpress LLC Tamoxifen | 10540-29-1 | 99.96% | 371.51 | 200 MG
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Tamoxifen is an orally active, selective estrogen receptor modulator (SERM) that blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. It is a potent Hsp90 activator, enhancing the Hsp90 molecular chaperone ATPase activity. It activates autophagy and induces apoptosis. Tamoxifen can also be dissolved in corn oil for use in inducing gene knockout in CreER transgenic mice.
- Orally active, selective estrogen receptor modulator (SERM)
- Blocks estrogen action in breast cells
- Can activate estrogen activity in bone, liver, and uterine cells
- Potent Hsp90 activator
- Enhances Hsp90 molecular chaperone ATPase activity
- Inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.1 μM and 1.8 μM
- Activates autophagy and induces apoptosis
- Can be dissolved in corn oil for gene knockout in CreER transgenic mice
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eMolecules 1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid | 100361-18-0 | 1G | Purity: 95%
Matrix Scientific | 1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid | 1G | 100361-18-0 | MFCD08458865
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Sigma Aldrich Fine Chemicals Biosciences 1,1′-Diethyl-2,2′-Cyanine Iodide | 977-96-8 | MFCD00011971 | 100mg
1,1′-Diethyl-2,2′-Cyanine Iodide | Purity: 97% | Mol Wt: 454.35 | 977-96-8 | MFCD00011971 | 100mg
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Medchemexpress LLC Sulfo-SPP | 452072-27-4 | 97.1% | 420.48 g·mol⁻1 | C14H16N2O7S3 | 5 MG
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Sulfo-SPP is a heterobifunctional, thiol-cleavable, membrane-impermeable crosslinker used as an ADC linker in bioconjugation research. It reacts selectively with primary amines and contains a cleavable disulfide linkage that enables release under reducing conditions. Supplied for research use only.
- Heterobifunctional thiol-cleavable crosslinker.
- Membrane impermeable sulfonate group improves aqueous solubility.
- Cleavable disulfide linkage for controlled release under reducing conditions.
- Suitable for antibody-drug conjugate and bioconjugation applications.
- Available in small pack sizes for research use.
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Ambeed 5Bromo2methoxypyrimidine
5-Bromo-2-methoxypyrimidine, 14001-66-2, 98%
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Ambeed Tetraphenylphosphonium chlorid
Tetraphenylphosphonium chloride, 2001-45-8, 97%
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